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Symbol
Name
ID
Thbd
thrombomodulin
MGI:98736
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Deep venous thrombosis
Hypercoagulability
Elevated erythrocyte sedimentation rate
Disease(s) Associated with THBD
rheumatoid arthritis
thrombophilia due to thrombomodulin defect

Mouse Phenotypes
abnormal leukocyte adhesion
increased spleen weight
increased megakaryocyte cell number
thrombocytopenia
abnormal spleen morphology
abnormal leukocyte physiology
Availability Mouse Genotype
Thbdtm1Wlr/Thbdtm1Wlr
Thbdtm2.1Emc/Thbdtm2.1Emc
Thbdtm2Emc/Thbdtm2Emc
Thbdtm1Wlr/Thbdtm2Rdr
Tg(Tek-cre)1Ywa/0
Thbdtm2Rdr/Thbdtm2Wlr  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory